CGP 52608

CGP 52608
	File:CGP 52608.svg
Names
	IUPAC name 3-Methyl-1-[(4-oxo-3-prop-2-enyl-1,3-thiazolidin-2-ylidene)amino]thiourea
Identifiers
CAS Number	87958-67-6;
3D model (JSmol)	Interactive image;
ChemSpider	4589397;
ECHA InfoCard	Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).
E number	Lua error in Module:Wikidata at line 880: attempt to index field 'wikibase' (a nil value).
PubChem CID	6509863;
UNII	QS3ABF85TR check;
CompTox Dashboard (EPA)	{{#property:P3117}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value).;
	InChI InChI=1/C8H12N4OS2/c1-3-4-12-6(13)5-15-8(12)11-10-7(14)9-2/h3H,1,4-5H2,2H3,(H2,9,10,14)/b11-8- Key: DDYJDIHOSRTMSE-FLIBITNWBI;
	SMILES S=C(N\N=C1/SCC(=O)N1C\C=C)NC;
Properties
Chemical formula	C8H12N4OS2
Molar mass	244.33 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

CGP 52608 is a selective ligand of the RAR-related orphan receptor alpha.^[1] It has been used as a biochemical tool to investigate nuclear and membrane signaling of melatonin.^[1] CGP 52608 has also been reported to possess antiarthritic activity.^[2] The pharmaceutical company Novartis brought it to clinical trials for rheumatoid arthritis, but development was discontinued in 2006.^[3]

CGP 52608 contains a thiazolinidinedione group.^[4]

References

^ ^a ^b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).

CGP+52608 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)