CENPI

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Centromere protein I is a protein that in humans is encoded by the CENPI gene.^[1]^[2]

Function

The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.^[2] CENPI is a target gene of the transcription factor E2F.^[3] Additionally, CENPI expression is increased in breast cancer and this has been shown to cause chromosome instability in breast cancer cells.^[3]

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Human CENPI genome location and CENPI gene details page in the UCSC Genome Browser.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.