CDC23
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Cell division cycle 23 homolog (S. cerevisiae), also known as CDC23, is a protein that, in humans, is encoded by the CDC23 gene.[1]
Function
[edit | edit source]The CDC23 protein shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.[1]
Interactions
[edit | edit source]CDC23 has been shown to interact with CDC27.[2][3]
References
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External links
[edit | edit source]- Human CDC23 genome location and CDC23 gene details page in the UCSC Genome Browser.
Further reading
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