CCNG2
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Cyclin-G2 is a protein that in humans is encoded by the CCNG2 gene.[1][2]
Function
[edit | edit source]The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.[2]
Interactions
[edit | edit source]CCNG2 has been shown to interact with PPP2CA.[3]
References
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External links
[edit | edit source]- Human CCNG2 genome location and CCNG2 gene details page in the UCSC Genome Browser.
Further reading
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