CASP8AP2
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). CASP8-associated protein 2 is a protein, that in humans is encoded by the CASP8AP2 gene.[1][2][3][4]
Function
[edit | edit source]This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Researches of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex, that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.[4]
Interactions
[edit | edit source]CASP8AP2 has been shown to interact with TRAF2.[5]
References
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Further reading
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External links
[edit | edit source]- CASP8AP2 human gene location in the UCSC Genome Browser.
- CASP8AP2 human gene details in the UCSC Genome Browser.
