CARD10
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Caspase recruitment domain-containing protein 10 is a protein in the CARD-CC protein family that in humans is encoded by the CARD10 gene.[1][2][3]
Function
[edit | edit source]The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in signaling through highly specific protein-protein homophilic interactions. CARDs induce nuclear factor kappa-B (NF-κB; MIM 164011) activity through the IKK (e.g., IKBKB; MIM 603258) complex. CARD9 (MIM 607212), CARD10, CARD11 (MIM 607210), and CARD14 (MIM 607211) interact with BCL10 (MIM 603517) and are involved in NF-κB signaling complexes. Except for CARD9, these CARD proteins are members of the membrane-associated guanylate kinase (MAGUK) family.[supplied by OMIM][3]
Interactions
[edit | edit source]CARD10 has been shown to interact with BCL10.[4]
References
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External links
[edit | edit source]- Human CARD10 genome location and CARD10 gene details page in the UCSC Genome Browser.
Further reading
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