CACYBP
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene.[1][2][3]
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[3]
Protein Interactions
[edit | edit source]CACYBP has been shown to interact with SKP1A[4] and SIAH1.[1]
The CacyBP/SIP complex instead, is known to be a part of stress respons, since it interacts with chaperone HSP90.[5]
References
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External links
[edit | edit source]- Human CACYBP genome location and CACYBP gene details page in the UCSC Genome Browser.
Further reading
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