Butalamine
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| Clinical data | |
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| E number | {{#property:P628}} |
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| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 29: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C18H28N4O |
| Molar mass | 316.449 g·mol−1 |
| 3D model (JSmol) | |
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Butalamine is a vasodilator.[1]
Synthesis
[edit | edit source]The reaction of benzamidoxime (1) with chlorine and subsequent reaction with cyanamide (3) gives 5-amino-3-phenyl-1,2,4-oxadiazole (4).[2][3][4] Base catalyzed alkylation with dibutylaminoethyl chloride (5) completes the synthesis of butalamine (6).
Synthesis of butalamine
References
[edit | edit source]- ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- ^ Aron-samuel Jan Marcel Didier, FR3334M (1965 to Jan Marcel).
- ^ Japan. Pat., 76 108 068, (1976); CA, 87, 5981b
- ^ Aron-Samuel Jan Marcel Didier, Sterne Jean Jacques, U.S. patent 3,338,899 (1967 to).
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