Bulboid corpuscle
| Bulboid corpuscle | |
|---|---|
 End-bulb of Krause. | |
| Details | |
| Identifiers | |
| Latin | corpuscula bulboideum |
| TA98 | Lua error in Module:Wikidata at line 746: attempt to index field 'wikibase' (a nil value). |
| TH | {{#property:P1694}} |
| TE | {{#property:P1693}} |
| FMA | {{#property:P1402}} |
| Anatomical terminology [[[d:Lua error in Module:Wikidata at line 865: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]] | |
The bulboid corpuscles (end-bulbs of Krause, Krause corpuscles) are cutaneous receptors in humans and other animals.
The end-bulbs of Krause were named after the German anatomist Wilhelm Krause (1833–1910).[1][2]
Function
[edit | edit source]The end-bulbs of Krause were thought to be thermoreceptors, sensing cold temperatures, but in early research their function remained unknown.[3] Recently optogenetic studies revealed their role in sexual stimulation and mating behavior in mice:
"Optogenetic activation of male Krause corpuscle afferent terminals evoked penile erection, while genetic ablation of Krause corpuscles impaired intromission and ejaculation of males as well as reduced sexual receptivity of females. Thus, Krause corpuscles, which are particularly dense in the clitoris, are vibrotactile sensors crucial for normal sexual behavior."[4]
Structure
[edit | edit source]They are minute cylindrical or oval bodies, consisting of a capsule formed by the expansion of the connective-tissue sheath of a medullated fiber, and containing a soft semifluid core in which the axis-cylinder terminates either in a bulbous extremity or in a coiled-up plexiform mass.
Location
[edit | edit source]End-bulbs are found in the conjunctiva of the eye (where they are spheroidal in shape in humans, but cylindrical in most other animals), in the mucous membrane of the lips and tongue, and in the epineurium of nerve trunks.
Krause corpuscles are found in the penis and the clitoris[5] and sometimes are referred to as genital corpuscles;[6] in these situations they have a mulberry-like appearance, being constricted by connective-tissue septa into from two to six knob-like masses.[citation needed]
In the synovial membranes of certain joints, e. g., those of the fingers, rounded or oval end-bulbs occur, and are designated articular end-bulbs.
References
[edit | edit source]
This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)
- ^ synd/2425 at Whonamedit?
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- ^ Qi, L., Iskols, M., Greenberg, R.S. et al. Krause corpuscles are genital vibrotactile sensors for sexual behaviours. Nature (2024). Krause corpuscles are genital vibrotactile sensors for sexual behaviours, Nature, June 19, 2024
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External links
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