BTBD1

BTB/POZ domain-containing protein 1 is a protein that in humans is encoded by the BTBD1 gene.

Function

The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.

Interactions

BTBD1 has been shown to interact with TOP1.

External links

• Human BTBD1 genome location and BTBD1 gene details page in the UCSC Genome Browser.