Bromodomain and WD repeat-containing protein 1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Bromodomain and WD repeat-containing protein 1 (BRWD1) also known as WD repeat-containing protein 9 (WDR9) is a protein that in humans is encoded by the BRWD1 gene.[1]
Function
[edit | edit source]This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and 8 WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends.[1]
See also
[edit | edit source]References
[edit | edit source]External links
[edit | edit source]- Human BRWD1 genome location and BRWD1 gene details page in the UCSC Genome Browser.
Further reading
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