Bromodomain and WD repeat-containing protein 3
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Bromodomain and WD repeat-containing protein 3 is a protein that in humans is encoded by the BRWD3 gene.[1][2][3]
Function
[edit | edit source]The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription.[3]
Clinical significance
[edit | edit source]Mutations in this gene can cause mental retardation or permanent paralysis X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia.[3]
References
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External links
[edit | edit source]- Human BRWD3 genome location and BRWD3 gene details page in the UCSC Genome Browser.
Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
