BRMS1
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Breast cancer metastasis suppressor 1 is a protein that in humans is encoded by the BRMS1 gene.[1][2]
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines.[3] The protein encoded by this gene localizes primarily to the nucleus, and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.[2]
References
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- ^ a b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- ^ Penn State Researchers Find Breast Cancer Metastasis Suppressor Gene
External links
[edit | edit source]- Human BRMS1 genome location and BRMS1 gene details page in the UCSC Genome Browser.
Further reading
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