BAM15

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BAM15
File:BAM15.png
Names
Preferred IUPAC name
N5,N6-Bis(2-fluorophenyl)[2,1,3]oxadiazolo[4,5-b]pyrazine-5,6-diamine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
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  • InChI=1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24)
    Key: OEGJBRZAJRPPHL-UHFFFAOYSA-N
  • C1=CC=C(C(=C1)NC2=NC3=NON=C3N=C2NC4=CC=CC=C4F)F
Properties
C16H10F2N6O
Molar mass 340.294 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

BAM15 is a novel mitochondrial protonophore uncoupler capable of protecting mammals from acute renal ischemic-reperfusion injury and cold-induced kidney tubule damage.[1][2] It is being studied for the treatment of obesity[3] sepsis,[1][4] and cancer.[5][6]

References

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