Arylformamidase
| arylformamidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.1.9 | ||||||||
| CAS no. | 156229-75-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an arylformamidase (EC 3.5.1.9, AFMID) is an enzyme that catalyzes the chemical reaction
- N-formyl-L-kynurenine + H2O formate + L-kynurenine
Thus, the two substrates of this enzyme are N-formyl-L-kynurenine and H2O, whereas its two products are formate and L-kynurenine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is aryl-formylamine amidohydrolase. Other names in common use include kynurenine formamidase, formylase, formylkynureninase, formylkynurenine formamidase, formamidase I, and formamidase II. This enzyme participates in tryptophan metabolism and glyoxylate and dicarboxylate metabolism.
References
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