Abraxis BioScience

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Abraxis BioScience
IndustryPharmaceutical
Founded2001; 25 years ago (2001) in Los Angeles, California[1]
FounderDr. Patrick Soon-Shiong
Defunct2010 (2010)
Headquarters,
United States
Key people
  • Mr. Rick Click (Chief Information Officer and Global IT Officer)
  • Dr. Nguyen V. Dat Ph.D. (vice president of Clinical Research)
ProductsProtein-based therapeutics and technologies for treatment of cancer and other critical illnesses
BrandsAbraxane
ServicesCancer drugs
RevenueIncrease US$359 million (2009)[2]
Decrease US$−113 million (2009)[2]
Decrease US$−104 million (2009)[2]
Total assetsDecrease US$1.068 billion (2009)[2]
Total equityDecrease US$846 million (2009)[2]
OwnerCelgene
Number of employees
885 (2009)[2]

Abraxis BioScience was a global biopharmaceutical, and nano-medicine company that developed treatments for critically ill patients. It had over 2000 employees worldwide in 2007. Abraxis's portfolio included the world's first protein-based nanoparticle chemotherapeutic compound, called nab Technology.[3] From this the company developed Abraxane, a treatment for metastatic breast cancer.[4]

In 2010, Abraxis BioScience was acquired by Celgene Corporation.[5]

History

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Abraxis was incorporated in 2001 in Los Angeles.[1] It was formerly known as American Pharmaceutical Partners (APP), which as known for its injectable oncology, anti-infective and critical care.[6] Besides cancer treatments, it provided treatment for multiple sclerosis, Alzheimer's, and some cardiovascular diseases.[1] It had manufacturing plants in Melrose Park, Illinois and Phoenix, Arizona.[1] By 2005, Dr. Patrick Soon-Shiong merged American BioScience and the publicly-held APP, naming it Abraxis BioScience.[7] Under this new name, seventy-four trials were undertaken to test Abraxane against various cancer targets.[7] The drug, which was approved by the FDA in 2005, was the subject of a litigation (Elan Pharma v. Abraxis BioScience) for patent infringement.[8] In 2008, Abraxis was ordered to pay $55.2 million to Elan.[8]

In August 2007, Abraxis announced it would again undergo a restructuring to separate its "hospital-based products business" from its "proprietary products business" into two public companies; this would involve the merging of Abraxis Oncology and Abraxis Research sub-units to form a new Abraxis Bioscience (Abraxis Bioscience, Inc., NasdaqABII), and the spinoff of Abraxis Pharmaceutical Products (APP, Inc., NasdaqAPPX).[9] This reorganization was completed in November 2007.[10] During the reorganization, the new Abraxis Bioscience was known briefly as New Abraxis.[10]

In 2010, Abraxis BioScience was acquired by Celgene Corporation.[5] Per Celgene's website, as of at least 2016 Abraxis no longer exists as a named division within Celgene.[citation needed]

References

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  1. ^ a b c d Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  2. ^ a b c d e f Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  3. ^ Abraxis BioScience, 2008, "Nab Technology", 10/11/2009
  4. ^ Hoovers. Archived 2015-09-24 at the Wayback Machine
  5. ^ a b Celgene, 30 June 2010, "Celgene To Acquire Abraxis BioScience Inc." (press release), 8/6/2015.
  6. ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  7. ^ a b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  8. ^ a b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  9. ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
  10. ^ a b Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
[edit | edit source]

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