ATF7IP
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Activating transcription factor 7-interacting protein 1 is a protein that in humans is encoded by the ATF7IP gene.[1][2][3]
Interactions
[edit | edit source]ATF7IP has been shown to interact with MBD1.[4] In mice with T cell-specific deletion of Atf7ip, the protein has been shown to play a role in regulating T helper 17 cell (Th17) differentiation due to increased IL-2 production upon stimulation of the T cell receptor (TCR). This TCR stimulation occurs through deposition of H3K9me3, a repressive histone mark.[5][6]
References
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Further reading
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External links
[edit | edit source]- Human ATF7IP genome location and ATF7IP gene details page in the UCSC Genome Browser.
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Activating transcription factor 7-interacting protein 1 (ATF7IP)
