ARL2
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.[1][2][3]
Function
[edit | edit source]- The ADP-ribosylation factor (ARF) genes are small GTP-binding proteins of the RAS superfamily. ARL2 is a member of a functionally distinct group of ARF-like genes.[3]
- In photoreceptors, ARL2 participates in the trafficking of lipidated membrane-associated proteins.[4]
- There is an evidence that increased activity of ARL2 protein is strongly correlated with increased mitochondria fusion, while loss of ARL2 activity results in a decreased rate of fusion.[5]
Interactions
[edit | edit source]ARL2 has been shown to interact with Protein unc-119 homolog,[6] TBCD[7][8] and PDE6D.[9][10]
References
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External links
[edit | edit source]- Human ARL2 genome location and ARL2 gene details page in the UCSC Genome Browser.
Further reading
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