ARID5B
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene.[1][2][3]
Alternative names for this gene include Modulator recognition factor 23.
Genomics
[edit | edit source]The gene is located on the long arm of chromosome 10 (10q21.2) on the 'plus' strand. It spans 195,261 base pairs in length. It encodes a protein of predicted length and molecular weight of 1188 amino acids and 132.375 kilodaltons respectively.
Clinical importance
[edit | edit source]Through genome wide association studies (GWAS), some of the single nucleotide polymorphisms (SNPs) located in this gene has been noticed to be significantly associated with susceptibility [4][5][6] as well as treatment outcomes [7] of childhood acute lymphoblastic leukaemia in ethnically diverse populations.
References
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External links
[edit | edit source]- Human ARID5B genome location and ARID5B gene details page in the UCSC Genome Browser.
Further reading
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