ARHGEF9
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Rho guanine nucleotide exchange factor 9 is a protein that in humans is encoded by the ARHGEF9 gene.[1][2][3]
Function
[edit | edit source]ARHGEF9 belongs to a family of Rho-like GTPases that act as molecular switches by cycling from the active GTP-bound state to the inactive GDP-bound state. These proteins are key regulators of the actin cytoskeleton and are involved in cell signaling.[supplied by OMIM][3]
Interactions
[edit | edit source]ARHGEF9 has been shown to interact with GPHN[4] and SMURF1.[5]
References
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External links
[edit | edit source]- Human ARHGEF9 genome location and ARHGEF9 gene details page in the UCSC Genome Browser.
Further reading
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