APOM
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| ApoM | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | ApoM | ||||||||
| Pfam | PF11032 | ||||||||
| Pfam clan | CL0116 | ||||||||
| InterPro | IPR022734 | ||||||||
| |||||||||
Apolipoprotein M is an apolipoprotein and member of the lipocalin protein family that in humans is encoded by the APOM gene.[1][2][3] It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Two transcript variants encoding two different isoforms have been found for this gene, but only one of them has been fully characterized.[3] It lacks an external amphipathic motif and is uniquely secreted to plasma without cleavage of its terminal signal peptide.[4] The average molecular weight is 21253 Da, and the monoisotopic molecular weight is 21239 Da.
References
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Further reading
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External links
[edit | edit source]- Applied Research on apoM
- Human APOM genome location and APOM gene details page in the UCSC Genome Browser.
- Overview of all the structural information available in the PDB for UniProt: O95445 (Human Apolipoprotein M) at the PDBe-KB.
