APOBEC3D
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Probable DNA dC->dU-editing enzyme APOBEC-3D is a protein that in humans is encoded by the APOBEC3D gene.[1][2]
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA.[2]
References
[edit | edit source]Identification of APOBEC3DE as another antiretroviral factor from the human APOBEC family. Dang Y, Wang X, Esselman WJ, Zheng YH. J Virol. 2006 Nov;80(21):10522-33. doi: 10.1128/JVI.01123-06. Epub 2006 Aug 18.
External links
[edit | edit source]- Human APOBEC3D genome location and APOBEC3D gene details page in the UCSC Genome Browser.
Further reading
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