Apolipoprotein A-II

ApoA-II
File:PDB 1l6l EBI.jpg structures of apolipoprotein a-ii and a lipid surrogate complex provide insights into apolipoprotein-lipid interactions
Identifiers
Symbol	ApoA-II
Pfam	PF04711
InterPro	IPR006801
SCOP2	1l6k / SCOPe / SUPFAM
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Apolipoprotein A-II is a protein that in humans is encoded by the APOA2 gene. It is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.

Interactions

ApoA-II has been shown to interact with phospholipid transfer protein.

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.

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Statin pathway edit

External links

• Human APOA2 genome location and APOA2 gene details page in the UCSC Genome Browser.