ALDH8A1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Aldehyde dehydrogenase 8 family, member A1 also known as ALDH8A1 is an enzyme that in humans is encoded by the ALDH8A1 gene.[1]
Function
[edit | edit source]This protein belongs to the aldehyde dehydrogenase family of enzymes. It was originally thought to play a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. However, bioinformatics and experimental work has shown that it is more likely the aldehyde dehydrogenase of the kynurenine pathway, oxidizing 2-aminomuconate semialdehyde to 2-aminomuconic acid.[2] Two transcript variants encoding distinct isoforms have been identified for this gene.[3]
References
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External links
[edit | edit source]- Human ALDH8A1 genome location and ALDH8A1 gene details page in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
