AKAP3
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). A-kinase anchor protein 3 is an enzyme that in humans is encoded by the AKAP3 gene.[1][2][3]
Function
[edit | edit source]The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.[3]
Interactions
[edit | edit source]AKAP3 has been shown to interact with:
References
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External links
[edit | edit source]- Human AKAP3 genome location and AKAP3 gene details page in the UCSC Genome Browser.
Further reading
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