ABLIM1
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Actin binding LIM protein 1, also known as ABLIM1, is a protein which in humans is encoded by the ABLIM1 gene.[1][2]
Function
[edit | edit source]This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.[1]
Interactions
[edit | edit source]ABLIM1 has been shown to interact with LDOC1.[3]
References
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External links
[edit | edit source]- Human ABLIM1 genome location and ABLIM1 gene details page in the UCSC Genome Browser.
Further reading
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