4-hydroxybenzoate polyprenyltransferase

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4-hydroxybenzoate polyprenyltransferase
Identifiers
EC no.2.5.1.39
CAS no.9030-77-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a 4-hydroxybenzoate polyprenyltransferase (EC 2.5.1.39) is an enzyme that catalyzes the chemical reaction

a polyprenyl diphosphate + 4-hydroxybenzoate diphosphate + a 4-hydroxy-3-polyprenylbenzoate

Thus, the two substrates of this enzyme are a polyprenyl diphosphate and 4-hydroxybenzoate, whereas its two products are diphosphate and 4-hydroxy-3-polyprenylbenzoate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. This enzyme participates in ubiquinone biosynthesis.[1]

Nomenclature

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The systematic name of this enzyme class is polyprenyl-diphosphate:4-hydroxybenzoate polyprenyltransferase. Other names in common use include:

  • nonaprenyl-4-hydroxybenzoate transferase,
  • 4-hydroxybenzoate transferase,
  • p-hydroxybenzoate dimethylallyltransferase,
  • p-hydroxybenzoate polyprenyltransferase,
  • p-hydroxybenzoic acid-polyprenyl transferase,
  • p-hydroxybenzoic-polyprenyl transferase, and
  • 4-hydroxybenzoate nonaprenyltransferase

References

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