R-spondin 3
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). R-spondin-3 is a protein that in humans is encoded by the RSPO3 gene.[1][2][3]
Function
[edit | edit source]This gene encodes a member of the thrombospondin type 1 repeat gene superfamily. In addition, the protein contains a furin-like cysteine-rich region. Furin-like repeat domains have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases.[3]
During embryonic development, RSPO3 is expressed in the tail bud and the posterior presomitic mesoderm of the embryo. In tissue engineering, R-spondin 3 has been used to differentiate pluripotent stem cells into paraxial mesoderm progenitors[4]
References
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Further reading
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