Rnd2
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Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Rnd2 is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rnd subgroup of the Rho family of GTPases.[1] It is encoded by the gene RND2.[2]
Function
[edit | edit source]It contributes to regulating the organization of the actin cytoskeleton in response to extracellular growth factors (Nobes et al., 1998).[supplied by OMIM][3]
This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking.
Clinical significance
[edit | edit source]The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1.[2]
Interactions
[edit | edit source]Rnd2 has been shown to interact with:
References
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Further reading
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