Precorrin-8X methylmutase
| precorrin-8X methylmutase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| File:1i1h.png | |||||||||
| Identifiers | |||||||||
| EC no. | 5.4.99.61 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a precorrin-8X methylmutase (EC 5.4.99.61) is an enzyme that catalyzes the chemical reaction
- precorrin-8X hydrogenobyrinate
Hence, this enzyme has one substrate, precorrin 8X, and one product, hydrogenobyrinate.
This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is precorrin-8X 11,12-methylmutase. Other names in common use include precorrin isomerase, hydrogenobyrinic acid-binding protein and CobH. This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in aerobic bacteria.
See also
[edit | edit source]Structural studies
[edit | edit source]As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1F2V, 1I1H, 1OU0, 1V9C, 2AFR, and 2AFV.
References
[edit | edit source]- ^ Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
- Lua error in Module:Citation/CS1/Configuration at line 2172: attempt to index field '?' (a nil value).
Lua error in mw.title.lua at line 392: bad argument #2 to 'title.new' (unrecognized namespace name 'Portal').