Neamine

Neamine
Clinical data
Other names	Neomycin A
Identifiers
	IUPAC name (1R,2R,3S,4R,6S)-4,6-Diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-α-D-glucopyranoside;
CAS Number	3947-65-7;
PubChem CID	72392;
DrugBank	DB04808;
ChemSpider	65325;
UNII	5981U00LY0;
E number	{{#property:P628}}
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Chemical and physical data
Formula	C12H26N4O6
Molar mass	322.362 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O([C@H]1[C@H](O)[C@@H](O)[C@H](N)C[C@@H]1N)[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2N)CN;
	InChI InChI=1S/C12H26N4O6/c13-2-5-8(18)9(19)6(16)12(21-5)22-11-4(15)1-3(14)7(17)10(11)20/h3-12,17-20H,1-2,13-16H2/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/m1/s1; Key:SYJXFKPQNSDJLI-HKEUSBCWSA-N;

Neamine (neomycin A) is a degradation product of the aminoglycoside antibiotic neomycin.^[1] Several derivatives of neamine are active against susceptible and resistant Gram-positive and Gram-negative bacteria.^[2]

References

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