Nucleoporin 88
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Nucleoporin 88 (Nup88) is a protein that in humans is encoded by the NUP88 gene.[1][2]
Function
[edit | edit source]The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.[2]
Interactions
[edit | edit source]NUP88 has been shown to interact with NUP98.[3]
References
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Further reading
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