Keratin 10
Lua error in Module:Infobox_gene at line 53: attempt to index field 'wikibase' (a nil value). Keratin, type I cytoskeletal 10 also known as cytokeratin-10 (CK-10) or keratin-10 (K10) is a protein that in humans is encoded by the KRT10 gene.[1][2][3] Keratin 10 is a type I keratin.
Function
[edit | edit source]Keratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.[3]
Interactions
[edit | edit source]Keratin 10 has been shown to interact with AKT1.[4]
See also
[edit | edit source]- 34βE12 (keratin 903)
References
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Further reading
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