Interposed nucleus
| Interposed nucleus | |
|---|---|
| Details | |
| Identifiers | |
| Latin | nucleus interpositus anterior, nucleus interpositus posterior |
| TA98 | Lua error in Module:Wikidata at line 746: attempt to index field 'wikibase' (a nil value). |
| TH | {{#property:P1694}} |
| TE | {{#property:P1693}} |
| FMA | {{#property:P1402}} |
| Anatomical terms of neuroanatomy [[[d:Lua error in Module:Wikidata at line 865: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]] | |
The interposed nucleus is the combined paired globose and emboliform nuclei, (deep cerebellar nuclei) on either side of the cerebellum.[1][2] It is located in the roof of the fourth ventricle, lateral to the fastigial nucleus. The emboliform nucleus is the anterior interposed nucleus, and the globose nucleus is the posterior interposed nucleus.[3]
The interposed nucleus is responsible for coordinating agonist/antagonist muscle pairs, and therefore a lesion in this area causes tremor.
Anatomy
[edit | edit source]The interposed nucleus is located in the paravermis of the cerebellum.[citation needed]
The interposed nucleus is smaller than the dentate but larger than the fastigial nucleus.[citation needed]
Afferents
[edit | edit source]The interposed nuclei receives Purkine cell terminal afferents from the paravermal cortex of the spinocerebellum, as well as collaterals of cerebellar afferents from the restiform body and ventral spinocerebellar tract.[2]
It receives input from the ipsilateral posterior external arcuate fibers (cuneocerebellar tract) and the dorsal spinocerebellar tract, which originate in the accessory cuneate nucleus and the posterior thoracic nucleus, respectively.[citation needed]
Efferents
[edit | edit source]Afferents from the interposed nuclei leave the cerebellum through superior cerebellar peduncle. They project to:[2]
- contralateral (magnocellular division of) the red nucleus (→ rubrospinal tract). The red nucleus is the main target of tne interposed nuclei.
- ipsilateral ventral lateral nucleus of thalamus (→ premotor cortex and primary motor cortex → lateral corticospinal tract).
The rubrospinal and lateral corticospinal tracts are subsequently involved in control of the distal musculature of the extremities.
Function
[edit | edit source]The interposed nucleus modulates muscle stretch reflexes of proximal limb muscles, and is also required in delayed Pavlovian conditioning.[4]
References
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External links
[edit | edit source]- https://web.archive.org/web/20080405060224/http://www.lib.mcg.edu/edu/eshuphysio/program/section8/8ch6/s8ch6_30.htm
- http://www.neuroanatomy.wisc.edu/cere/text/P5/interp.htm
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