Galactoside

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A galactoside is a glycoside containing galactose. The H of the OH group on carbon-1 of galactose is replaced by an organic moiety.[1]

File:ONPG structure.png
Structure of ONPG, an example of a β-galactoside.

Depending on whether the glycosidic bond lies "above" or "below" the plane of the galactose molecule, galactosides are classified as α-galactosides or β-galactosides.

A β-galactoside is a type of galactoside in which the glycosidic bond lies above the plane of the galactose residue. The most commonly recognized and used β-galactoside in biochemistry is lactose.[citation needed] However, other chemicals, such as ONPG, are known, but these are typically synthesized for biochemical assays.

Galactosides play significant roles in metabolic processes of many organisms and are hydrolyzed by a class of enzymes called galactosidases and are classified according to what type of glycosidic linkage on the galactoside they will break.[2] For example, enzymes that hydrolyze the β-galactoside glycosidic bond are called β-galactosidases, while those that hydrolyze the α-galactoside glycosidic bond are known as α-galactosidases.[2]

References

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