Copper ibuprofenate
Anhydrous
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Monohydrate
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R = (CH3)2CHCH2C6H4CH(CH3)-
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| Names | |
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| IUPAC name
bis[2-(4-isobutylphenyl)propionato]copper(II)
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C52H68Cu2O8 | |
| Molar mass | 948.200 g·mol−1 |
| Appearance | Blue Powder |
| Density | 1.299 g/cm3[1] |
| Slightly soluble | |
| Solubility in isopropanol | Slightly soluble |
| Related compounds | |
Related compounds
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Copper aspirinate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Copper ibuprofenate is a coordination complex consisting of copper(II) and the conjugate base of ibuprofen. The compound is prepared by the reaction of sodium ibuprofenate with copper(II) sulfate.[2][3]
Copper ibuprofenate adopts a typical Chinese lantern structure, as seen for many transition metal carboxylate complexes. X-ray crystallography reveals a polymer with a bonding motif very similar to that of copper(II) trifluoroacetate.[1]
It has been suggested that copper complexes of anti-inflammatory drugs are more active than the parent drug[4] and produce fewer gastrointestinal side-effects.[5] In 2008, a United States patent was issued for the utilization of ibuprofenate complexes (including copper ibuprofenate) as a wood preservative.[6]
References
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