2022–2023 mpox outbreak in Chile

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2022–2023 mpox outbreak in Chile
File:2022 monkeypox outbreak cases in Chile.svg
Confirmed and suspected cases by region.
DiseaseMpox
Virus strainMonkeypox virus
(West African clade)
LocationChile
Index caseSantiago de Chile
Arrival dateJune 17, 2022 (2022-06-17)–present (3 years, 10 months, 1 week and 3 days)
Confirmed cases1,442[1]
Suspected cases26[1]
Hospitalized cases400[1]
Recovered1,442[1]
Deaths
3[1]
Government website
Monkeypox Epidemiological Situation Report
(in Spanish)
Suspected cases have not been confirmed by laboratory tests as being due to this strain, although some other strains may have been ruled out.

The 2022–2023 mpox outbreak in Chile is a part of the outbreak of human mpox caused by the West African clade of the monkeypox virus. The outbreak reached Chile on 17 June 2022.[2]

Background

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Mpox (/ˈɛmpɒks/, EM-poks; originally known as monkeypox)[3] is an infectious viral disease that can occur in humans and other animals. Symptoms include a rash that forms blisters and then crusts over, as well as fever and swollen lymph nodes. The illness is usually mild, and most infected individuals recover within a few weeks without treatment. The time from exposure to the onset of symptoms ranges from three to seventeen days, and symptoms typically last from two to four weeks. However, cases may be severe, especially in children, pregnant women, or people with suppressed immune systems.[4][5][6]

The disease is caused by the monkeypox virus, a zoonotic virus in the genus Orthopoxvirus. The variola virus, which causes smallpox, is also in this genus.[5] Human-to-human transmission can occur through direct contact with infected skin or body fluids, including sexual contact.[5] People remain infectious from the onset of symptoms until all the lesions have scabbed and healed.[4] The virus may spread from infected animals through handling infected meat or via bites or scratches.[4] Diagnosis can be confirmed by polymerase chain reaction (PCR) testing a lesion for the virus's DNA.[5]

Vaccination is recommended for those at high risk of infection.[5] No vaccine has been developed specifically against mpox, but smallpox vaccines have been found to be effective.[7] There is no specific treatment for the disease, so the aim of treatment is to manage the symptoms and prevent complications.[5][8] Antiviral drugs such as tecovirimat can be used to treat mpox,[5] although their effectiveness has not been proven.[9]

An ongoing outbreak of mpox was confirmed on May 6, 2022, beginning with a British resident who, after travelling to Nigeria (where the disease is endemic), presented symptoms consistent with mpox on April 29, 2022. The resident returned to the United Kingdom on May 4, creating the country's index case of the outbreak.[10] The origin of several of the cases of mpox in the United Kingdom is unknown. Some monitors saw community transmission taking place in the London area as of mid-May,[11] but it has been suggested that cases were already spreading in Europe in the previous months.[12]

Transmission

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File:Stages of monkeypox lesion development.jpg
Stages of lesion development.

A large portion of those infected were believed to have not recently traveled to areas of Africa where mpox is normally found, such as Nigeria, the Democratic Republic of the Congo as well as central and western Africa. It is believed to be transmitted by close contact with sick people, with extra caution for those individuals with lesions on their skin or genitals, along with their bedding and clothing. The CDC has also stated that individuals should avoid contact and consumption of dead animals such as rats, squirrels, monkeys and apes along with wild game or lotions derived from animals in Africa.[13]

In addition to more common symptoms, such as fever, headache, swollen lymph nodes, and rashes or lesions, some patients have also experienced proctitis, an inflammation of the rectum lining. CDC has also warned clinicians to not rule out mpox in patients with sexually transmitted infections since there have been reports of co-infections with syphilis, gonorrhea, chlamydia, and herpes.[14]

History

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The first case of infection was recorded on June 17 in Santiago de Chile after an adult with a history of travel to Europe presented symptoms table

Statistics

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File:Metropolitan-region-monkeypox.svg
Cases in Metropolitan Region
Cases of mpox 23-09-22
Region Cases
File:Flag of the Metropolitan Region, Chile.svg Santiago Metropolitan Region 732
File:Flag of La Araucanía Region.svg Araucanía 10
File:Flag of Antofagasta Region, Chile.svg Antofagasta 14
File:Flag of Valparaiso Region, Chile.svg Valparaíso Region 25
File:Flag of O'Higgins Region, Chile.svg O'Higgins 6 [15]
File:Flag of Coquimbo Region, Chile.svg Coquimbo 21 [16]
File:Flag of Los Lagos Region, Chile.svg Los Lagos Region 3 [17]
File:Flag of Maule, Chile.svg Maule Region 6 (+2)
File:Flag of Biobío Region, Chile.svg Biobío Region 14
File:Flag of Los Ríos, Chile.svg Los Ríos Region 2 (+1)
File:Flag of Ñuble Region, Chile.svg Ñuble Region 2 (+1)
Every 4 days (Tuesday and Friday)
Date Total Cases Cases in RM Cases outside of RM New / daily avg
02-08-22 68 62 6
05-08-22 91 83 9 (+3) 5
09-08-22 126 116 10 (+1) 8
12-08-22 141 130 11 (+1) 3
15-08-22 189 176 13 (+2) 12
19-08-22 207 194 13 4
23-08-22 270 194 13 15
26-08-22 344 317 27 (+14) 18
30-08-22 381 354 27 9
02-09-22 450 404 46 (+19) 17
06-09-22 484 46 8
23-09-22 842 732 110

Notes

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References

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